Osteoarthritis – anti-inflammatory and analgesic drug use

Because of the dense structure and a relatively poor blood supply to the bone can become a reservoir for germs. Therefore, we can’t ignore even seemingly trivial infections. Unhealed bone infection may persist for many years.

Overall, the inflammatory processes taking place in the system osteoarthritis can be divided into infectious and non-infectious.

In the case of arthritis disease process may be affected by both the elements of bone, cartilage and synovium that. Sometimes this is accompanied by bursitis joint. The specific type of image depends on the individual case and inflammation. Not always occur to address all elements of the joint and inflammatory changes can be variously pronounced in its individual parts. In the case of infectious inflammation of bone marrow cavity, it usually takes epiphyses and around, and in the case of non-infectious inflammation at the joint area.

Infectious inflammation

In the case of osteoarthritis infective agents can be bacteria and fungi, and in the case of joints as some viruses. Infection can have a variety of symptoms – from the very non-specific, as fatigue or weight loss, the typical signs of inflammation such as redness, pain, swelling and fever. Risk factors include infection of the tissues adjacent to the bone, damage to bones and joints of the interruption of tissues, some systemic diseases, such as diabetes.

Treatment of fungal or bacterial infections comprises administering said anti-microbial agents. Due to the penetration of a dense bone structure of the drug to the site of infection may be difficult. Typically, bone infections require hospital treatment after determining the sensitivity of the agent to a drug. But sometimes it happens that it is necessary to amputate the limb portion.

Noninfectious inflammation

They may be various reasons for rheumatoid disease, or connective tissue diseases and other metabolic diseases. In the terminology adopted in our degenerative changes are not counted in inflammatory lesions. While there is a form of inflammatory degenerative changes, however, they are generally classified as a distinct disease entity. Slightly more pragmatic terminology is English, in which the term arthritis covers any irregularities joints due to inflammation (including infectious), metabolic and degenerative. This approach is so reasonable that clinical symptoms and treatment of these pathologies are often similar.

The predominant symptoms are continuous or periodic pain and more or less impairment of joint function. Sometimes the pain can be suspected as a kind of disease, but the exact diagnosis requires a clinical examination supplemented by imaging studies and laboratory. For example, pain associated with a feeling of morning stiffness may indicate arthritis, pain after prolonged while still appearing to movements of the degenerative changes might suggest.

For the treatment of infectious inflammation typically involves the administration of antibiotics. Sometimes it is necessary to perform a surgical procedure to deliver the drug to the bone marrow cavity, where because of the good blood supply to the infection can easily develop. In the case of infectious arthritis is sometimes necessary to remove purulent fluid from the joint cavity.

Rheumatoid diseases

In the case of rheumatoid arthritis, ankylosing spondylitis, or some other rheumatoid diseases or systemic wrong is essential to the immune response to its own tissues. Treatment is very diverse and unfortunately in most cases not fully effective; mechanisms of these diseases are not sufficiently known. In some embodiments, the rheumatic disease is not possible to implement the treatment of the primary disease cause elimination. Apply the symptomatic treatment to alleviate the symptoms and allow the patient as normal operation.

Degenerative changes

Although degenerative changes, with the exception of the inflammatory form, do not meet the criteria of the inflammatory process, it is worth to mention them. In these diseases, the treatment is almost entirely symptomatic, whereas the heavier it is necessary to change the damaged cartilage graft endoprosthesis or insertion.

Anti-inflammatory and analgesic drugs

As mentioned earlier, the most common symptom of all cases of arthritis or bone – regardless of etiology – is a pain. To alleviate it class of drugs NSAIDs are commonly used. They can provide the basis for therapy in the treatment of symptomatic non-infectious arthritis, in other cases they are used sometimes as a supplement to the basic treatment.

Many non-steroidal anti-inflammatory drug belongs to a class of OTC drugs (Naproxen, ibuprofen) or prescription drugs (meloxicam). Their use should be consulted with a doctor because of the possible interactions and side effects. Sometimes patients apply excessive amounts of drugs in this group linking the formulations of the same mechanism of action, generally increases and gives adverse therapeutic effect. If necessary, it should be combined analgesics acting in a different way; reduces the risk of adverse effects. This is important especially with prolonged use of anti-inflammatory drugs and analgesics. It is worth remembering that the broad inflammatory processes in the system osteoarthritis often have a chronic condition.